Article library

Education from the institute.

60 plain-language articles on skin cancer types, biopsies and pathology, procedures, treatment, prevention, and life after a diagnosis. Each lists its sources.

Types of skin cancer · 5 min read

Melanoma warning signs and what happens after you point one out

How to recognize a spot that could be melanoma, and what a doctor does from the first look through the biopsy result.

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Types of skin cancer · 5 min read

Basal cell carcinoma: a patient guide

What basal cell carcinoma looks like, why it rarely spreads yet still needs treatment, how doctors treat it, and the odds of getting another.

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Types of skin cancer · 5 min read

Squamous cell carcinoma of the skin: a patient guide

How cutaneous squamous cell carcinoma appears, what makes a tumor high risk, how doctors treat it, and what follow-up involves.

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Types of skin cancer · 5 min read

Actinic keratosis: the rough spot that can become skin cancer

What actinic keratoses are, how often they turn into squamous cell carcinoma, and how spot treatments differ from field treatments.

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Types of skin cancer · 5 min read

Atypical moles and dysplastic nevi: what the words mean

What doctors mean by atypical or dysplastic moles, how pathology grading affects re-excision, and what these moles say about melanoma risk.

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Types of skin cancer · 5 min read

Merkel cell carcinoma: a guide to a rare, fast-moving skin cancer

Who gets Merkel cell carcinoma, how to recognize it, how doctors stage it, and how surgery, radiation, and immunotherapy are used.

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Types of skin cancer · 5 min read

Skin cancer in people with darker skin

Skin cancer is less common in darker skin but often found later. Learn where it tends to appear, what it looks like, and why sun protection still counts.

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Types of skin cancer · 5 min read

Acral and nail melanoma: melanoma of the palms, soles, and nails

How melanoma appears on the palms, soles, and under nails, why doctors often find it late, and how doctors biopsy and treat it.

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Types of skin cancer · 5 min read

Melanoma in situ and lentigo maligna: stage 0 explained

What stage 0 melanoma means, why the outlook is excellent, how surgeons choose margins, and what options exist when surgery is difficult.

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Types of skin cancer · 4 min read

Nodular and amelanotic melanoma: the ones that break the ABCDE rules

Some melanomas are raised, fast-growing, or pink instead of flat and dark. Learn the EFG rule and why a new, firm, growing bump needs a visit.

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Types of skin cancer · 5 min read

Mucosal melanoma: melanoma of the mouth, nose, anus, vulva and vagina

A rare melanoma unrelated to sun: where it starts, the symptoms that get mistaken for common problems, how its genetics differ, and how doctors treat it.

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Types of skin cancer · 2 min read

Understanding Ocular Melanoma

Where ocular melanoma develops, the known risk factors, and how it is diagnosed and treated.

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Diagnosis and pathology · 5 min read

Skin biopsy types and what to expect

How shave, punch, incisional, and excisional skin biopsies are done, why a doctor picks one, and what healing and results look like.

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Diagnosis and pathology · 4 min read

How to read a melanoma pathology report

A line-by-line guide to the terms on a melanoma pathology report, what each one means, and which ones change treatment.

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Diagnosis and pathology · 4 min read

Breslow depth, ulceration, and mitotic rate

The 3 microscope measurements that matter most in early melanoma, the AJCC thickness cutoffs, and how each one affects staging.

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Diagnosis and pathology · 4 min read

Melanoma staging explained, stage 0 through stage IV

What melanoma stages 0 through IV mean under the AJCC 8th edition system, which tests set the stage, and how to read survival figures.

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Diagnosis and pathology · 5 min read

Sentinel lymph node biopsy for melanoma, explained

What a sentinel lymph node is, who is usually offered the biopsy, how mapping works, the risks, and what a positive result leads to today.

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Diagnosis and pathology · 4 min read

Second opinions in skin pathology

Why moles and early melanomas are hard to diagnose, what research shows about pathologist agreement, and how a slide review works.

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Diagnosis and pathology · 4 min read

Molecular tests for moles and melanoma

The stains, chromosome tests, and gene expression tests used on difficult moles and melanomas, and what guidelines say about each.

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Diagnosis and pathology · 4 min read

Dermoscopy and mole mapping

How dermoscopy, total body photography, and digital mole monitoring work, who benefits, and what the evidence shows about accuracy.

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Diagnosis and pathology · 5 min read

AI tools and smartphone apps for skin checks

What artificial intelligence devices and phone apps can and can't do for skin cancer detection today, based on FDA decisions and published studies.

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Diagnosis and pathology · 5 min read

Moles and melanoma in children

What is normal for moles in childhood, how congenital and Spitz nevi behave, how rare pediatric melanoma is, and when to have a spot checked.

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Procedures · 5 min read

Wide local excision for melanoma

What happens in the main operation for melanoma, how the margin width is chosen from tumor thickness, and what recovery and the final pathology report involve.

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Procedures · 5 min read

Mohs surgery, step by step

A walk through the day of Mohs surgery: who qualifies, how the layers and lab checks work, cure rates, wound repair, and its use for melanoma in situ on the face.

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Procedures · 5 min read

Curettage, cryotherapy, and simple excision: office procedures for skin cancer

How scraping, freezing, and simple excision treat low-risk skin cancers and precancers, what healing looks like, and when doctors avoid them.

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Procedures · 5 min read

Creams and gels for skin precancers and thin skin cancers

What fluorouracil, imiquimod, tirbanibulin, and diclofenac treat, the skin reaction to expect week by week, and how the options compared in a head-to-head trial.

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Procedures · 5 min read

Photodynamic therapy for actinic keratoses and thin skin cancers

How a light-sensitizing drug plus a light source clears sun-damaged skin, what the visit feels like, the 48 hours of light avoidance, daylight PDT, and results.

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Procedures · 5 min read

Radiation therapy for skin cancer

When radiation is used for basal cell, squamous cell, Merkel cell, and melanoma skin cancers, the types and schedules, side effects, and the debate over its routine use.

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Procedures · 5 min read

Wound care and scars after skin surgery

Evidence-based aftercare for a skin surgery wound: petrolatum, bandages, bleeding, infection signs, activity limits, and how scars change over 12 months.

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Procedures · 5 min read

Reconstruction after skin cancer surgery

How surgeons repair the wound left by skin cancer removal, from natural healing to flaps, grafts, and staged repairs, who does the work, and what to expect over months.

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Procedures · 5 min read

Lymph node surgery for melanoma and the risk of lymphedema

Why full lymph node dissection is now uncommon after a positive sentinel node, when surgeons still do it, and how lymphedema is recognized, prevented, and treated.

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Treatment · 5 min read

Hedgehog inhibitors for advanced basal cell carcinoma: vismodegib and sonidegib

How vismodegib and sonidegib switch off the pathway that drives basal cell carcinoma, who takes them, verified trial results, side effects, and what comes next.

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Treatment · 5 min read

Treatment after melanoma surgery to lower the chance it comes back

How adjuvant immunotherapy and targeted therapy work after surgery for stage IIB, IIC and III melanoma, what trials found, and the side effect trade-off.

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Treatment · 5 min read

Immunotherapy before surgery for stage III melanoma

Why giving immunotherapy before surgery helps in stage III melanoma you can feel or see on scans, and what the S1801 and NADINA trials showed.

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Treatment · 5 min read

Immunotherapy side effects: what to watch for, organ by organ

How checkpoint inhibitors can inflame healthy organs, the symptoms that need a same-day call, how steroids treat them, and which effects are permanent.

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Treatment · 5 min read

BRAF and MEK inhibitors: targeted therapy pills for melanoma

What a BRAF V600 mutation means, the 3 approved pill combinations, their side effects, why resistance develops, and how doctors order them with immunotherapy.

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Treatment · 5 min read

TIL therapy and lifileucel (Amtagvi) explained

How tumor-infiltrating lymphocyte therapy is made from your own tumor, who may be a candidate, what the hospital stay involves, and what the evidence shows.

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Treatment · 5 min read

When melanoma spreads to the brain

How melanoma brain metastases are found and treated with radiosurgery, surgery, and immunotherapy, plus what to know about steroids, seizures, and driving.

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Treatment · 5 min read

Clinical trials for skin cancer: how they work and how to find one

What trial phases mean, how randomization and placebos are used in cancer studies, your rights as a participant, what insurance covers, and where to search.

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Treatment · 2 min read

Novel Treatments for Melanoma

How melanoma arises, the standard treatment options by stage, and the newer approaches now in development.

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Treatment · 2 min read

Treatment Options for Melanoma: Hope for the Future

Surgery, radiation, chemotherapy, immunotherapy, targeted treatment, and clinical trials, and when each is used.

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Treatment · 3 min read

Skin Cancers: Immunotherapy Options

How immunotherapy works, which drugs are used for melanoma, squamous cell, basal cell, and Merkel cell cancers, and the side effects to watch for.

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Prevention and risk · 5 min read

How to choose and use sunscreen

What SPF, broad spectrum, and water resistance mean, how much sunscreen to apply, and what the FDA says about ingredient safety.

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Prevention and risk · 4 min read

Tanning beds and melanoma

How much indoor tanning raises skin cancer risk, why a base tan fails to protect, what the law says, and how sunless tanners differ.

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Prevention and risk · 5 min read

The UV Index, shade, and sun-protective clothing

How to read the UV Index, use the shadow rule, pick UPF clothing, hats, and sunglasses, and account for windows, altitude, snow, and water.

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Prevention and risk · 5 min read

Vitamin D and sun protection

Why dermatologists suggest food and supplements for vitamin D, what studies show about sunscreen and vitamin D levels, and who may need a test.

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Prevention and risk · 5 min read

Melanoma genetics and family history

How family history affects melanoma risk, which inherited genes are known, who is offered genetic counseling, and what a test result changes.

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Prevention and risk · 5 min read

Skin cancer after an organ transplant

Why transplant medicines raise skin cancer risk, how often skin checks are done, and what is known about prevention and treatment options.

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Prevention and risk · 5 min read

Who gets melanoma: risk factors from strongest to weakest

The main melanoma risk factors in rough order of strength, how age and sex shape the numbers, and which risks a person can change.

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Prevention and risk · 5 min read

Nicotinamide (vitamin B3) and skin cancer prevention

What trials show about nicotinamide for preventing basal and squamous cell skin cancers, the usual dose, safety, and who may be offered it.

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Prevention and risk · 5 min read

What a sunburn does to your skin and how to care for it

What happens in skin cells during a sunburn, how to treat one at home, when to get medical care, and what past burns mean for skin cancer risk.

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Prevention and risk · 5 min read

Medicines that make your skin more sensitive to the sun

Which common medicines can cause sun reactions, what the 2 reaction types look like, what is known about skin cancer risk, and what to ask your prescriber.

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Prevention and risk · 5 min read

Skin cancer risk for people who work outdoors

How much working in the sun raises skin cancer risk, which jobs are affected, and the protections that workers and employers can put in place.

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Prevention and risk · 5 min read

Protecting your eyes and eyelids from the sun

How UV light harms the eyes and eyelids, how to pick sunglasses that protect, and how eyelid skin cancers look and are treated.

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Prevention and risk · 5 min read

UV through windows, in cars, and in everyday life

Which kinds of UV pass through car, office, and airplane windows, what screens and nail lamps emit, and how small daily exposures add up.

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Prevention and risk · 2 min read

Children and sun safety tips

Six practical ways to protect children, and yourself, from sun damage in every season.

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Living with skin cancer · 5 min read

Follow-up after melanoma: visits, scans, and self-exams

How often doctors see you after melanoma treatment by stage, when scans are used, how to check your own skin and lymph nodes, and what recurrence looks like.

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Living with skin cancer · 5 min read

Coping with a skin cancer diagnosis, fear of recurrence, and scan anxiety

What research shows about anxiety and depression after melanoma, practical ways to handle fear of recurrence and scan days, and where to find support.

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Living with skin cancer · 5 min read

Pregnancy and melanoma

How moles change in pregnancy, what studies show about melanoma outcomes, and how biopsy, surgery, and future pregnancy plans are handled.

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Living with skin cancer · 5 min read

What to expect at a full-body skin exam

How to prepare for a full-body skin exam, what the dermatologist checks, how privacy is handled, and what happens if a spot needs a biopsy.

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